Mohammed ishaq 3 deccan school of pharmacy 1, hyderabad, andhra pradesh, india. Therefore, search of nephroprotective herbs from medicinal plants has become important and need of the day. Antidiabetic, hematoprotective and nephroprotective effects. Phytochemical analysis of traditional medicinal plants and. Nephroprotective activity of alyssum meniocoides boiss. Antinephrotoxic activity of some medicinal plants from. The therapeutic efficacy of thai medicinal plants and traditional herbal medications has been scientifically proven and described in the literature by both thai and nonthai scientists. Nephroprotective effect of sonchus oleraceus extract against. Many medicinal plants exhibited nephroprotective effect of renal tissues against kidney injuries induced by gentamicin, paracetamol, profenofos, d galactosamine dgaln, chronicstress, sepsis and cytotoxic drugs. Hepatoprotective activity and nephroprotective activity of. Nephroprotective activity of pterocarpus marsupium germany. Biosci tech,vol 81,2017,801812 journal of bioscience and technology. Using ethnomedicinal plants is the oldest way of mankind to treat the several diseases.
In this study, alyssum meniocoides am boiss aqueous extract was extracted to investigate its nephroprotective activity on renal structural and biochemical changes in. But plants are having lot of phytochemicals which heal the kidney damages without and side effects. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh. According to acharya charak, mootra dosh vikar is tretised by punarnava, haritaki, shunthi, nagarmotha, shilajeet, gokshura, yavakshar etc. Anti diabetic medicinal plants open access journals.
The results showed that husk extract of zea mays has nephroprotective potential against injurious agents which may be due to the activities of its phytochemical components. Oxidative stress and the inflammatory process are involved in ischemiareperfusion ir injury. Antinephrotoxic activity of some medicinal plants from tribal rich pockets of odisha satyaranjan mishra, saumya ranjan pani, 1 and sabuj sahoo 2 k. Evaluation of nephroprotective activity of the methanolic extract of leaves of bauhinia variegata linn. The aim of this study is to evaluate the nephroprotective activity of defatted methanolic extract of two egyptian plants. This nephroprotective study carried out by gentamicin induced nephrotoxicity. The extracts are often used as nephroprotective activity such as aqueous, ethanolic, hydroalcoholic and methanolic extract are mainly used against commonly drug induced nephrotoxicity and some of the medicinal plants are cited in table 2 2638. Nephroprotective effect of herbal extract eurycoma.
Nephrotoxicity is a poisonous effect of some substances, both toxic chemicals and medication, on the kidneys. Experimental study of nephroprotective, nephrocurative and antioxidant activity of some medicinal plants yogesh chand yadav on. Medicinal plants make up the most important tool in curing a disease. Anthocephalus cadamba, aegle marmelos, emblica officinalis and moringa oleifera.
The results of this study indicate that extracts of leaves and plants of some medicinal plants have good potentials for use in kidney damage. They were housed in polypropylene cages and maintained under standard condi. Journal of medicinal plants studies anticancer, antiviral, antidiabetic, nephroprotective, antiinflammatory, antimicrobial etc. Mar 27, 2018 eucalyptus globulus are a prime source of global eucalyptus oil production. Introduction of medicinal plants species with the most traditional usage in alamut region. May 14, 2009 this study was conducted to establish the nephroprotective activity of plants. Medicinal plants possessed hepatoprotective activity through many mechanisms, included antioxidant properties of medicinal plants, enhancement of antioxidant defense superoxid dismutase, catalase and glutathione peroxidase activity12, reduced peroxidation34. Mar 01, 2010 medicinal plants make up the most important tool in curing a disease. This study was conducted to establish the nephroprotective activity of plants. Ibrahim, nizam institute of pharmacy and research centre, deshmukhi, pochampally, near ramoji film city, nalgonda508284, a.
Because when we use the chemical compounds may induce the side effects for the many organs of our body. Nephroprotective effect of herbal extract eurycoma longifolia. The present study investigates comparative antioxidant, anticancer activity and qualitative, quantitative and spectral characterization of phytochemicals present among aqueous and ethanolichydroethanolic leave extracts of four medicinal plants viz. Many medicinal plants have proved to be effective for hepatic and renal diseases. Antidiabetic, hematoprotective and nephroprotective. But with the abundance of phytochemical content found in the passion fruit peel extract, an extract that is likely to provide hepatoprotective activity and nephroprotective activity.
Evaluation of nephroprotective activity of the methanolic. Healthy male sprague dawley rats weight, 150 g to 200 g were procured from chaudhary charan singh university. An experience from north east india j pharm res phytochemical analysis of traditional medicinal plants and their antimicrobial activity. Deccan school of pharmacy 1, hyderabad, andhra pradesh, india. The nephroprotective activity is probably due to the presence of flavanoids in all the few medicinal plants. These plants have a wide use in traditional system of medicine.
Compared with 30 years ago, the average patient today is older, has more. Juglans mollis has been reported as having antioxidant activity, which could attenuate the damage caused by ir. A study has been conducted with the aim to find dose dependant effect of eucalyptus oil on diabetic mice induced with streptozotocin stz and analyze the. Nephroprotective ethnomedicinal action of selected indian. Antiinflammatory and nephroprotective activity of juglans. The results show the good nephroprotective herbal commonly used in tea and easily available medicinal plants for all peoples. Comparative phytochemical investigation, antioxidant and. A variety of medicinal plants and plant ex tracts have been reported for its significant nephroprotective activity in animal models 12. Ajpt nephroprotective potential of herbal medicines. Ethanolic extract of achyranthes aspera shows bronchoprotective effect in toluene diisocyanate tdi induced occupational asthma in wistar rats as reported by goyal et al.
Introduction drugs are a common source of acute kidney injury. Nephroprotective activity of ethanolic extract of orthosiphon. Mar 29, 2018 using ethno medicinal plants is the oldest way of mankind to treat the several diseases. Virani institute of pharmacy and research centre, badhada, savarkundla, gujarat, india. The present study was design to determine antioxidant potential, nephroprotective and nephrocurative activity of some medicinal against cisplatin induced. They were gm in albino rats, cisplatin in rabbits, mercuric chloride in mice, ethylene glycol in mice etc. Pcm is generally considered as safe but overdose of pcm can cause nephrotoxicity. This has been observed by estimating the bio markers and listed in the above table. This activity may be related to decreased levels of proinflammatory cytokines il1. In this study, bellis perennis l aqueous extract bp was extracted to investigate its hematoprotective and nephroprotective activities on renal structural. Review on nephroprotective activity study by different plant extract paoulomi chatterjee 1. Using of herbal plant extracts for the nephroprotective activity is the best method in the traditional medicine. Hepatoprotective and nephroprotective activity of phyllanthus.
This oil has therapeutic, flavoring, antimicrobial, and biopesticide properties. Nephroprotective activity of plumeria rubra pr against. Nephroprotective and antioxidant activities of caralluma. Traditionally, herbs have been used for the treatment of drug or toxininduced renal disorders and numerous medicinal plants were tested for nephroprotection effect in pcminduced nephrotoxicity model. Medicinal plants containing active chemical constituents are useful in prevention and treatment of. Ethnomedicinal plants are recommended for the prevention, control, and treatment of several diseases.
From different regions, varied plant species having potent nephroprotective activity area unit portrayed at intervals the subsequent section. Nephroprotective agents are the substances which possess protective activity against nephrotoxicity. Kansharitaki is also very helpful in motra dosha vikar as well as vatakaph odema7. It was proved by analyzing the biomarkers and enzymes level. Jul 26, 2019 to our knowledge, this is the first report of nephroprotective activity of j. Table no 1 list of plants having nephroprotective activity 333. The final results shows the ethonolic extracts of plants have good nephroprotective activity when compared with the standard drug. Medicinal plants have curative properties due to the presence of various complex chemical substances. Our study provides a basis for further identification of which molecules are responsible for this apparent nephroprotective activity of s. Phytochemical composition and in vitro antimicrobial and antioxidant activities of some medicinal plants. Eucalyptus globulus are a prime source of global eucalyptus oil production. Several reports have revealed that the hypoglycaemic activity of most antidiabetic medicinal plants has been attributed to the presence of saponins. The evaluation of saponin constituents of medicinal plants seems to be a logical way of searching for new drugs to treat this disease.
Feb 28, 2019 the hepatoprotective activity and nephroprotective activity of the passion fruit peel extract have never been reported in the research article. Antinephrotoxic activity of some medicinal plants from tribal rich pockets of odisha. Methanolic leaf extract of the plant has significant nephroprotective activity. Due to the rapid growth of global interest in use of medicinal plants, their effects and safety evaluation have become substantial. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh, india. Nephroprotective activity of husk extract of zea mays.
Many studies showed that the presence of antioxidant compounds in plants conferred them a nephroprotective activity 2 26 27. The hepatoprotective activity and nephroprotective activity of the passion fruit peel extract have never been reported in the research article. Many herbs have been proven to be effectual as nephroprotective. Medicinal plants as antiulcer agents t lakshmi srinivas, s mohana lakshmi, s neelufar shama, g koteswara reddy. This study aimed to test the effect of prosopis ruscifolia griseb. Nephrotoxicity should not be confused with the fact that some medications have a predominantly renal excretion and need their dose adjusted for the decreased renal function e. A large number of medicinal plants, natural products and. It also possess antioxidant activity and scientific research has shown that medicinal plants with such ability may possess nephroprotective effect. The activity of each may be affected by limitation of atp, compromise of function of enzyme protein or changes in the phospholipid.
Medicinal plants, nephroprotective agents, renal disorders. Nephroprotective activity of plumeria rubra pr against cisplatin induced nephrotoxicity in experimental rats 3 rd world congress on medicinal plants and natural products research october 0203, 2017 kuala lumpur, malaysia. Medicinal plants and herbs have long been a part of everyday life in thailand. The main objective of the present study was to investigate the nephroprotective activity of the medicinal plants caesalpinia bonduc and momordica dioica against cisplatininduced nephrotoxicity. Nephroprotective role of alcoholic extract of pterocarpus. An experience from north east india minakshi b, jharna d, chanbi devi e, nayan t, partha pk, kundal n. Shilajeet is help ful with take gomutra in motra dosha vikar. Methanolic leaf extract has reduced the increased creatinine levels when compared to the control group.
The result shown that the extract have very good protective effect in the control of creatinine, urea and uric acid. Lantana camara and cucurbita pepo and certain fractions derived from the defatted methanolic extract of l. Cisplatin is a highly effective chemotherapeutic agent. The result shown that the extract have very good protective effect. Various models have been used to substantiate the nephroprotective activity of herbals. Paracetamol pcm is a wellknown drug widely used for its analgesic and antipyretic properties. Ahvazi m, khalighisigaroodi f, charkhchiyan mm, mojab f, mozaffarian va, zakeri h. This effective diverse herb particularly hepatoprotective, used therapeutically by the unani attiba, since time immemorial in various disorders has been duly supported and validated by above mentioned in vitro. Nephroprotective effect of sonchus oleraceus extract. Nephroprotective and antioxidant activity of medicinal plants. Medicinal plants may serve as a vital source of potentially useful new compounds for the development of effective therapy to combat a variety of kidney problems.
This is the first report of nephroprotective activity of s. Ishak2, saad mohammed hussien ayoub3 1department of chemistry, college of applied and industrial science, university of bahri, khartoum, sudan. Medicinal plants possessed hepatoprotective activity. A large number of medicinal plants, natural products and dietary components have been evaluated as potential nephroprotective agents.
Nephroprotective drugs from traditionally used aboriginal. Moreover, the results obtained in our study are comparable with previously reported nephroprotective activity against gentamicin induced nephrotoxicity of plant species like tribulus terrestris and crataeva nurvala, ocimum. From different regions, varied plant species having potent nephroprotective activity area unit. We evaluated whether a methanolic extract of juglans mollis jm exhibits nephroprotective activity in a wistar rat model of ir injury.
Nephroprotective activity of methanolic extract of lantana. Plants have also been a major source of new drugs since the inception of modern pharmacology. Canarium schweinfurthii is a tropical plant which has been found useful in the treatment of various ailments such as diabetes mellitus, fever, constipation, malaria,diarrhoea and sexually transmitted diseases. Pharmacological and medicinal uses of achyranthes aspera 127 bronchoprotective activity.
Dec 12, 2016 the nephroprotective activity is probably due to the presence of flavanoids in all the few medicinal plants. Phytochemical analysis of traditional medicinal plants and their antimicrobial activity. A dose dependent hepatoprotective and nephroprotective. Table 1 lists selected plants used by aboriginal tribes all over canada for kidney diseases. Bauhinia variegate the antioxidant and nephroprotective effect in gentamicininduced nephrotoxicity of the ethanolic and aqueous extracts of root of bauhinia variegata. Nephroprotective and antioxidant activity of medicinal. Preliminary evaluation of hepatoprotective and nephroprotective effects of prosopis ruscifolia griseb. The extracts of ficus bengalensis, hemidesmus indica, sida retusa,ixora coccenia,green tea and terminalia chebula were screened invitro for their antioxidant activity.
This oil has got popularity because they are reported as pharmacologically active. Evaluation of phytoconstituents, nephroprotective and. The experiment was carried out in mice, 300 mgkg of acetaminophen, i. Abdelsalam3 1 department of botany, kohat university of science and technology, kohat, pakistan.
Clitoria ternateact, is an herbaceous medicinal plant used to treat, liver problems used analgesic and antipyretic agent which, at high doses, causes liver and kidney necrosis in man and animals. Antimicrobial activity of three medicinal plants artemisia indica, medicago falcata and tecoma stans tahir javid 1, muhammad adnan1, akash tariq1,basreen akhtar, riaz ullah2, naser m. Poacae also known as maize or corn, is an annual grass plant cultivated. Mostly, these are used for diuresis, renal stones and cleansing the kidneys. Antimicrobial activity of four medicinal plants used by. Antioxidant activity of some common medicinal plants. This crude extract was used for further animal studies. Nephroprotective activity of stem bark extracts of.
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